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Drug Research > Gene Expression
The following information is about Gene Expression.
Gene Expression Defined
The process by which a gene's coded information is converted into the structures present and operating in the cell. Expressed genes include those that are transcribed into mRNA and then translated into protein, and those that are transcribed into RNA but not translated into protein (e.g., transfer and ribosomal RNAs).
This definition is in context to Drug Research. See more contextual defintions for Gene Expression.
Oxygen key to 'cut and paste' of genes
Published July 3, 2009, 9:03 am, PhysOrg
(PhysOrg.com) -- An oxygen-sensitive enzyme has been found to play a key role in how genes create the many different proteins that make up our bodies.
Gene's novel role may provide key to treating liver and neurodegenerative diseases
Published July 3, 2009, 4:48 am, PhysOrg
Scientists at Singapore's Bioprocessing Technology Institute (BTI) have made a novel discovery about how the gene, "Fas-apoptosis inhibitory molecule" (FAIM), protects both immune and liver cells from apoptosis, or programmed cell death.
Gene's novel role may provide key to treating liver and neurodegenerative diseases
Published July 2, 2009, 6:13 pm, EurekAlert!
( Agency for Science, Technology and Research (A*STAR), Singapore ) Singapore scientists have made a novel discovery about how gene, "Fas-apoptosis inhibitory molecule", protects both immune and liver cells from programmed cell death. Their research is published in Cell Death and Differentiation.
New biomarkers of melanoma identified
Published July 2, 2009, 10:46 am, The Times of India
WASHINGTON: Scientists from Yale University have identified new biomarkers that will help develop more effective treatment strategies to fight melanoma, the most serious form of skin cancer.
Virus-Gene Therapy Combination Being Tested Against Melanoma
Published July 2, 2009, 8:10 am, Medical News Today
Researchers at the Moores UCSD Cancer Center are injecting a modified herpes virus into melanoma tumors, hoping to kill the cancer cells while also bolstering the body's immune defenses against the disease.
Inovio Biomedical, National Microbiology Laboratory, And University Of Pennsylvania To Evaluate Candidate DNA Vaccines ...
Published July 1, 2009, 9:49 pm, PharmaceuticalOnline
Inovio Biomedical Corporation, a leader in DNA vaccine design, development and delivery, announced today it has established a new collaboration with the National Microbiology Laboratory of the Public Health Agency of Canada and the University of Pennsylvania to further evaluate Inovio DNA vaccine candidates against swine influenza A (H1N1) virus.
Illumina Announces Preliminary Revenue for Second Quarter 2009
Published July 1, 2009, 1:01 pm, Business Wire via Yahoo! Finance
SAN DIEGO----Illumina, Inc. today announced, based on management's preliminary financial review, second quarter revenue of approximately $161 million compared to guidance of $168 to $173 million.
'Trojan' cells take on drug-resistant tumours
Published July 1, 2009, 10:13 am, New Scientist
Just one imitation horse was enough to conquer Troy, but two waves of "Trojan" cellular compartments are needed to destroy drug-resistant tumours in mice
Research Identifies Biomarker That Safely Monitors Tumor Response To New Brain Cancer Treatment
Published July 1, 2009, 8:30 am, redOrbit
Gene therapy technique developed in animal model by Cedars-Sinai research team uses immune cells to attack glioblastoma multiformeA specific biomarker, a protein released by dying tumor cells, has been identified as an effective tool in an animal model to gauge the response to a novel gene therapy treatment for glioblastoma mulitforme.
Biomarker That Safely Monitors Tumor Response To New Brain Cancer Treatment
Published July 1, 2009, 7:20 am, Science Daily
A specific biomarker, a protein released by dying tumor cells, has been identified as an effective tool in an animal model to gauge the response to a novel gene therapy treatment for glioblastoma mulitforme.
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Off-site Gene Expression Links, User Submitted
The following links have been collected through user bookmark submission in the Gene Expression category. Please note, because these resources are off-site we cannot guarantee the accuracy or quality of any information.
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- Gene Expression Atlas @ EBI: Large Scale Meta-Analysis of Public Microarray Data
Wed Jun 17
- Cell - Nature, Nurture, or Chance: Stochastic Gene Expression and Its Consequences: Gene expression is a fundamentally stochastic process, with randomness in transcription and translation leading to cell-to-cell variations in mRNA and protein levels. This variation appears in organisms ranging from microbes to metazoans, and its characteristic s depend both on the biophysical parameters governing gene expression and on gene network structure. Stochastic gene expression has important consequences for cellular function, being beneficial in some contexts and harmful in others. These situations include the stress response, metabolism, development, the cell cycle, circadian rhythms, and aging.
- Cell - Nature, Nurture, or Chance: Stochastic Gene Expression and Its Consequences: Gene expression is a fundamentally stochastic process, with randomness in transcription and translation leading to cell-to-cell variations in mRNA and protein levels. This variation appears in organisms ranging from microbes to metazoans, and its characteristic s depend both on the biophysical parameters governing gene expression and on gene network structure. Stochastic gene expression has important consequences for cellular function, being beneficial in some contexts and harmful in others. These situations include the stress response, metabolism, development, the cell cycle, circadian rhythms, and aging.
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- Gene Expression: This site is great for viewing gene expression through transcription and translation.
Fri May 29
- Gene Expression Omnibus (GEO): a gene expression/mol ecular abundance repository supporting MIAME compliant data submissions, and a curated, online resource for gene expression data browsing, query and retrieval.
- Sex-Dependent Liver Gene Expression Is Extensive and Largely Dependent upon Signal Transducer and Activator of Transcription 5b (STAT5b): STAT5b-Depende nt Activation of Male Genes and Repression of Female Genes Revealed by Microarray Analysis
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